What we are able to study from sequencing 1 million human genomes with large information

The primary draft of the human genome was published 20 years ago in 2001, took almost three years and value between US$500 million and $1 billion. The Human Genome Project has allowed scientists to learn, nearly finish to finish, the three billion pairs of DNA bases – or “letters” – that biologically outline a human being.

That venture has allowed a brand new technology of researchers like me, at the moment a postdoctoral fellow on the Nationwide Most cancers Institute, to establish novel targets for cancer treatments, engineer mice with human immune systems and even construct a webpage where anyone can navigate the entire human genome with the identical ease with which you employ Google Maps.

The primary full genome was generated from a handful of nameless donors to attempt to produce a reference genome that represented greater than only one single particular person. However this fell far in need of encompassing the wide diversity of human populations in the world. No two persons are the identical and no two genomes are the identical, both. If researchers needed to grasp humanity in all its variety, it could take sequencing 1000’s or tens of millions of full genomes. Now, a venture like that’s underway.

There is a huge amount of genetic variation between people around the globe.
Credit score: Gerd Altmann from Pixabay